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Drugs delivered to the nasal mucosa act as quickly as intravenous injections.
The nasal route avoids hepatic first pass metabolism that vastly reduces the bioavailability of some oral medications. The Go Medical nasal PCA device is a hand activated spray that is highly acceptable to patients.
The spray is delivered in small droplet form, reducing the volume of drug reaching the nasopharynx. Applications include; pre-emptive analgesia (e.g. dressing changes for patients with burns) moderate to severe pain in children and adults, and palliative care.