These sanitary TFF (tangential flow filtration) systems are ideal for concentration or separation of biological solutions and suspensions in developmental or production uses.
Optimal flow path design and easy-to-use failsafe controls safeguard your biopharmaceutical products and maximize recovery.
The ProFlux systems provide interchangeable use of Millipore's cartridges, Pellicon 2 Cassettes or Spirals cartridges. Low hold-up volumes allow high concentration factors and maximum product recovery. Desalting or buffer exchange require no additional equipment.
A vacuum-tight reservoir permits continuous diafiltration. To process larger volumes, connect to an auxiliary vessel.
The ProFlux A series incorporates PLC control and built-in VDU with touch screen. This displays a color process diagram and operating parameters.
The unit also control pressures, filling , process start, concentration, diafiltration and end of process when configured with level transmitter. Temperature control is available on units equipped with heat exchanger.
Data acquisition package and network interface is available for all Series A systems providing full access (password protected) for operation or viewing of the process from a control room or office PC.
ProFlux systems are mounted on a trolley/cart for mobility. The systems are supplied with one cartridge connection position, allowing selection of optimal membrane and flow channel specifications for your needs. You can select tangential flow ultrafiltration or microfiltration techniques.
By specifying the appropriate optional manifold kit, the installed membrane area may be increased as indicated in the table on this page. Cartridge adapters may also be required.
ProFlux systems are self- contained, with reservoir (and spray ball), controller, and pump skid. All flowpath pipe work, valves, and reservoir components are of sanitary design and compatible with CIP procedures.
- Heat exchanger/closed-loop processing
- Level control with automated diafiltration control function
- Permeate control with secondary pump
- Manifold Extension Kit
- Remote operation and data acquisition package for PC via RS 422 interface (adapts to RS 232 serial port)
- Automated - repeatable performance
- Real-time process diagram with digital indication of process parameters (A series)
- Time-saving automation for processing of large volumes
- Low minimum process volumes for high concentration ratios
- Suitable for cold-room operation.
Units are shipped assembled. All systems have been pre-assembled, calibrated and tested at the factory.
Cartridges, manifolds and housings require installation on site regardless of system size. Piping, power supply, external wiring and interface connections with outside equipment are not included.