Medivac Exhaled Breath Condensates – Turbo ...

Medivac - Exhaled Breath Condensates – Turbo Deccs System

Exhaled Breath Condensates – Turbo Deccs System

The "Turbo DECCS System" was designed and developed specifically to facilitate the collection of Exhaled Air Condensate (CAE / EBC), and is the most complete, versatile, simple and cheap system on the market.

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The core of the “System” is a “family” of collection circuits named DECCS used together with special devices that complete the “System”, such as: TURBO which is a condenser for the controlling cooling of the test tubes; AAV used to discriminate the alveolar part of the exhaled air; VOLMET 20 a volumetric measurement device of the treated air. In addition, only for Europe, it is available the pH KIT, used to measure on the field and at the moment of the collection, the pH of the collected sample.

Furthermore, it is the only System that allows the use of two or more condenser devices in series or in parallel, to perform collections with different condensation temperatures at the same time.

METHOD FOR THE COLLECTION OF THE EBC

The method is simple, it doesn’t require special skills and it is not invasive. For the conscious patients (cooperative), the collection is made by exhaling into the mouthpiece of the disposable collection kit, while in case of unconscious patients (under assisted respiration or ventilated) the collection is automatic and it is performed when the entrance of the collection disposable unit is connected to the endotracheal tube (or to the mask) and the exit to the return tube of the “ventilator”.

The exhaled air is funneled into the DECCS circuit and go through the collection test tube, previously cooled at a pre-set temperature (between 0 and -10°), on whose internal faces condenses because it is a saturated vapeur (99% of water). Approximately, for the collection of 1,5/3,0 ml of EBC, it should be processed about 75-110 L of total exhaled air and the estimated time is 10-15min.

The collected condensate, in previously measured doses, must be stored in the freezer at the lowest possible temperature
(recommended – 80°C / – 112°F because it guarantees the stability of many mediators contained).

Subsequently thawed and subjected to analysis with diagnostic methods such as MS-GC , IMS, fluorimetry, ELISA among others, may allow the diagnosis of lung diseases through the identification of the volatile, non-volatile or low volatility compounds present in exhaled breath, in addition to the determination of inflammation biomarkers and oxidative stress, produced by the cells of the airways. It represents the ideal method for non-invasive study of lung diseases and of the effects of early-induced inhaled pneumo-toxic substances.